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Saturday, May 16, 2020 | History

3 edition of The role of herpesviruses in atherogenesis found in the catalog.

The role of herpesviruses in atherogenesis

The role of herpesviruses in atherogenesis

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  • 12 Currently reading

Published by Harwood Academic Publishers in Amsterdam .
Written in English

    Subjects:
  • Arteriosclerosis -- Etiology,
  • Atherosclerosis -- etiology.,
  • Herpesviridae -- pathogenicity.,
  • Herpesviruses.

  • Edition Notes

    Includes bibliographical references and index.

    Statementedited by David P. Hajjar and Stephen M. Schwartz.
    SeriesAdvances in vascular biology -- v. 4
    ContributionsHajjar, David P., Schwartz, Stephen M.
    Classifications
    LC ClassificationsRC692 .R647 1999
    The Physical Object
    Paginationxiv, 162 p. :
    Number of Pages162
    ID Numbers
    Open LibraryOL20729658M
    ISBN 109057023210

    Atherosclerosis is a disease in which the inside of an artery narrows due to the buildup of plaque. Initially, there are generally no symptoms. When severe, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney problems, depending on which arteries are affected. Symptoms, if they occur, generally do not begin until middle cations: Coronary artery disease, . The effect of elevated homocysteine levels on adrenergic vasoconstriction of human resistance arteries: The role of the endothelium and reactive oxygen species Marilyn J. Cipolla, Williamson, Mark L. Nehler, Lloyd M. Taylor, John M. Porter.

    His research focused on the role of herpes virus infection in atherogenesis, and delineating the role of nitric oxide in inflammation and cholesterol trafficking. From to the present, he has garnered more than $70 million dollars in grant support from extramural sources. An avian herpesvirus is known to cause atherosclerosis in chickens. The same virus can induce a proliferative disease, malignant lymphoma, suggesting that this agent may also have transforming potential and thus stimulate the proliferation of arterial smooth muscle cells, a prominent feature of by:

      Atherosclerosis is a chronic, multifactorial disease in which inflammatory processes have long been known to be involved. Heat shock proteins (HSPs) are a Cited by:   The potential clinical importance of a causal role of HAV infection in atherosclerosis and the fact that the cross-sectional design of the present study does not permit definitive conclusions regarding causality should stimulate the initiation of further studies to determine whether HAV is indeed a causative factor in by:


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The role of herpesviruses in atherogenesis Download PDF EPUB FB2

Role of Herpesviruses in Atherogenesis (Advances in Vascular Biology Series) [Hajjar, David P, Schwartz, Stephen M] on *FREE* shipping on qualifying offers. Role of Herpesviruses in Atherogenesis (Advances in Vascular Biology Series).

There is evidence that suggests that the herpesvirus has a role in many vascular disorders. This text discusses the role that herpesviruses play in the pathophysiological processes related to cholesterol metabolism and intracellular trafficking, matrix production, thrombosis, and others.

Author(s): Hajjar,David P; Schwartz,Stephen M; DeBakey,Michael E(Michael Ellis), Title(s): The role of herpesviruses in atherogenesis/ edited by David P. Hajjar and Stephen M. Schwartz. Country of Publication: Netherlands Publisher: Amsterdam: Harwood Academic Publishers, © Although many authors proved the presence of viral DNA in arterial wall tissue, the role of herpesviruses in the origin and progress of atherogenesis still remains unclear.

Objectives: The aim of this study was to confirm the presence of viral DNA in arterial wall and to associate the presence of these viruses with the development of atherosclerosis in patients with ischemic heart disease (IHD).Cited by: Fabricant CG, Fabricant J () Marek’s disease virus-induced atherosclerosis and evidence for a herpesvirus role in the human vascular disease.

In: Calnek BW, Spencer JL (eds) International Symposium on Marek’s disease, American Association on Avian Pathology, pp – Google ScholarCited by: 7. Recent studies have brought renewed interest to the hypothesis that infection plays a role in the pathogenesis of Alzheimer’s disease (AD).

In particular, herpesviruses such as herpes simplex virus-1 (HSV-1) and human herpesvirus-6 (HHV-6) have had an extensive history of association with : Mary Alice Allnutt, Steven Jacobson. To examine the possible role of viruses in the etiology of atherosclerosis, we searched for the presence of viral genomes in arterial tissues by in situ hybridization.

Because chickens infected with Marek disease virus, a herpesvirus, develop atherosclerotic lesions after infection, we looked for the presence of herpesvirus or parts thereof in human artery wall tissue, particularly in Cited by: Herpesvirus probes were used on specimens of aortic wall removed from patients undergoing coronary bypass surgery.

Evidence for the presence of herpes simplex viral mRNA was obtained in 13 specimens. Some of the specimens positive for herpes simplex virus appear to represent early stages in by:   The discovery by Virchow more than years ago that atheroma contained a yellow fatty substance, later identified as cholesterol by Windaus, suggested a role for lipids in the pathogenesis of atherosclerosis.

Indeed, the goal of this chapter is to focus on the role of lipids and lipoproteins in the pathogenesis of atherosclerosis as well as their critical roles in risk assessment and as targets.

Her research interests are the regulation of smooth muscle cell behaviour in atherosclerosis and restenosis, most recent studies have focused on the role of cell-cell contacts and the Wnt pathway. Dr George has written over 50 scientific original articles and was awarded the British Atherosclerosis Society John French Lecture in Cholesterol plays an important role in the atherogenesis, which has been extensively studied (Nicholls & Lundman, ).

Although lipids have a key role in the development of atherosclerotic plaques, a direct connection between atherogenesis and lipids remains uncertain. The Herpesviruses provides information pertinent to all the herpesviruses, with emphasis on the classification, morphology, replication, physical–chemical properties, and immunological relationships of all the herpesviruses.

This book presents Book Edition: 1. In this Review, we describe three pathways by which microbiota might affect atherogenesis. First, local or distant infections might cause a harmful inflammatory response that aggravates plaque Cited by: The role of fluid mechanics in atherogenesis: Proceedings from a specialists meeting Unknown Binding – January 1, See all formats and editions Hide other formats and editions.

Enter your mobile number or email address below and we'll send you a link to download the free Kindle App. Manufacturer: [Ohio State University Experiment Station]. Fundamental issues remain unresolved regarding the possible contribution of viruses to vascular pathology, as well as the role of the immune system in regulating these processes.

Here we Cited by: The chapters on the epidemiology and latency of HSV, and on the glycoproteins specified by HSV and CMV, set the stage for the discussions of the immunobiology and pathogenesis of human herpesvirus infections in Volume 4.

The epidemiology of HSV is the basis of our understanding of the spread and survival of this virus in the human populations. This book introduces and reviews several topics for each human herpesvirus.

One of the most important features of the book is that it covers aspects of both basic research and clinical medicine. Herpesviridae, a family of double-strand DNA viruses, has unique biological features by which these viruses establish latency after primary infection. Herpes viruses are capable of HERV transactivation, and both virus groups are known to interact with each other inducing synergistic immune responses.

This review presents further evidence on association of HERVs and herpesviruses with MS. Enter your mobile number or email address below and we'll send you a link to download the free Kindle App. Author: Tomasz Brudek.

Inflammation plays a key role in the initiation and progression of atherosclerosis and can be caused by multiple agents, including increased concentration of circulating low-density lipoprotein (LDL) cholesterol. Areas of the arterial wall affected by atherosclerosis are enriched with lymphocytes and dendritic cells (DCs).

Atherosclerotic plaques contain a variety of proinflammatory immune Author: Dimitry A. Chistiakov, Dmitry A. Kashirskikh, Victoriya A. Khotina, Andrey V.

Grechko, Alexander N. The Thrombotic Process in Atherogenesis (Advances in Experimental Medicine & Biology) by Chandler, A.B. et al (ed) and a great selection of related books, art. Herpesviridae is a large family of DNA viruses that cause infections and certain diseases in animals, including humans.

The members of this family are also known as family name is derived from the Greek word herpein ("to creep"), referring to spreading cutaneous lesions, usually involving blisters, seen in flares of herpes simplex 1, herpes simplex 2 and herpes zoster (shingles).Class: incertae sedis.

Atherosclerosis: The New View. It causes chest pain, heart attack and stroke, leading to more deaths every year than cancer. The long-held conception of how Author: Peter Libby.Abstract—Although definitive proof of a causal role of infection contributing to atherogenesis is lacking, multiple investigations have demonstrated that infectious agents evoke cellular and molecular changes supportive of such a er, both Chlamydia pneumoniae and cytomegalovirus exacerbate lesion development in animal models of atherosclerosis and by: